Anti-Human/Mouse PBR Antibody - 100 µl

Anti-PBR Polyclonal Antibody
 

The peripheral-type benzodiazepine receptor (PBR) is a ubiquitous protein involved in the regulation of cholesterol transport from the outer to inner mitochondrial membrane. Thought to play a role in the formation of the mitochondrial permeability transition (PT) pore involved in apoptotic mechanisms, PBR is also present in abundance in tumors, in aggressive breast cancer cell lines, and in metastatic human breast tumor biopsy sections.

Immunogen: The anti-PBR antibody was developed in rabbits against an internal sequence of the PBR protein consisting of amino acids 71 to 88 of the human PBR sequence. The specificity of the antibody was assessed in steroidogenic cells and in mitochondrial extracts.
 
Source: Rabbit
 
Specificity: Cat# 6361-PC-100 recognizes mouse, rat, and human PBR protein.
Cat# 6362-PC-100 recognizes mouse PBR protein
 
 
Preparation: Anti-PBR antibody is provided as rabbit anti-seral. 
 
Applications: Immunohistochemistry
Western blotting
Starting recommended dilution for Western blot is 1:1,000; for immunohistochemistry, 1:250.
 
 
Control: Recombinant PBR protein (Cat# 6360-025-01) available separately.
 
Storage: Stable for at least 3 years when stored at -20°C. For long term storage, divide into aliquots and avoid repeated freeze-thawing