C-reactive protein 0.1 mg C-reactive protein 0.05 mg
Source: Chicken
Purity: Immunoaffinity Purified
Clonality: Polyclonal
Crossreactivity: Human
Format: Phosphate-Buffered Saline. No preservatives added.
Storage: 4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw.
Stability: 6-12 months at -20 degree C.
Shipping: Products may be shipped on ice pack or dry ice. CRP ANTIBODY TARGET DESCRIPTION: Synonym Names for CRP antibody: CRP; PTX1; C-reactive protein
Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosi and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Cofactor: Binds 2 calcium ions per subunit.
Subunit: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 noncovalently bound subunits.
Subcellular Location: Secreted protein.
Tissue Specificity: Found in plasma.
Induction: The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.
Mass Spectrometry: MW=23028; METHOD=MALDI; RANGE=19-224; NOTE=Ref.13.
Mass Spectrometry: MW=22930; METHOD=MALDI; RANGE=19-223; NOTE=Ref.13.
Miscellaneous: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.
Similarity: Belongs to the pentaxin family.
Similarity: Contains 1 pentaxin domain.
C-reactive protein reacts with human.
OMIM: 123260; gene. [NCBI / EBI]
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