Pathway: Bt Folate Metabolism WP1075 86818

210, 30345, 87, 94, 105, 141...59, 6145, 97, 253, 275, 30997144, 2111974084146, 27927, 188, 24916795, 17811ReactionSelenoproteinsNegative EffectBiomarker forCleavageis composed ofMetabolitesProtein*CofactorsFrom intracellular part to the plasmaOverarching processLipoprotein melabolismLEGENDSelenium statusLipid peroxidationEnzymesConversionProtein tyrosine nitrationNecessary stimulationProcess or metabolism involved in Se PathwayTranscription factorOther proteinsGlycogenesisBindingCofactor conversionProstaglandins metabolismCatalysisInhibitionStimulationMicronutrientsProtein with polymorphismIntracellularMethylation reactionsDNA oxidationNovo purine biosynthetic pathwayApoptosisPlasmaF2-IsoprostaneFOLR1NFKB1PGE1PGE2PGE1FOLR38-Isoprostaglandin F2aThromboxane B2TP53PGF2aThromboxane B2FOLR2Thromboxane A2PGF2aSLC46A1CCL2SLC19A1F2-Isoprostane8-Isoprostaglandin F2aCCL2FOLR4RELAPGE2NFKB2225, 28931322119611, 18, 105, 183, 188...313196230, 2963724293, 22531319693, 22537221225, 28931319629637, 82, 225242MAT1ADHFRMTRMTRRMTHFD2AHCYMTHFD1SHMT268, 213, 291, 321178171, 17827235, 72, 133115, 178301, 321CBS291, 318NADP+NADP+NADP+NADP+NADP+NADP+NADP+NOSMPOCATMPO97, 23124, 120, 252, 30924, 120, 252, 309230CysteineCysteineF7SERPINE1PLGPLGF7F2F2PLATPLATSERPINE1123176, 326123123123176, 326139, 176123123139, 176GPX4H2O25,10-Methylene-THF(11R)-hydroxymethylene-THFGARFGAR5-Formyl-THF5,10-Methenyl-THFDihydrofolate10-Formyl-THF(11S)-hydroxymethylene-THF17895, 17872, 17895, 17817817817817872Folate5-methyl-THFFolate5-methyl-THF11, 34, 39, 72, 154...72, 21372ECSODECSODRFK79H2OGPX3GPX3CTH291Heme97, 231, 318THF72NADPHNADPHNADPHNADPHNADPHNADPHNADPHGPX6ManganeseManganeseFolic acidFolic acid68, 72, 10468, 72, 104GPX2GPX 1RNS40, 97MTHFRSHMT1MTHFSGART17868, 7217895, 178HomocysteineHomocysteine27, 45, 52, 139, 213...139SOD1Pyridoxal 5'-phosphatePyridoxal 5'-phosphate42, 11642, 116, 230L-ArginineGlycineSerineGlycine171, 178171, 178171, 178154SCARB1APOBTAGVLDL/APOBAPOA1VLDLAPOA1ACTHDL/SAACholesterolHDL-CACTSAA2SAA3oxLDLVLDL-TAGHDL-CHDLFMNHDL/APOA1TAGSAA4VLDL-TAGSAA1HDLLDLAPOBABCA1CholesterolLDLLDLRVLDLAPOA1oxLDL90, 18129421121139, 21118144, 144, 252, 26690, 18118131, 233207, 21139, 211181181207, 211212207, 21121144, 144, 252, 266207, 211, 2123121118139, 44, 144, 252, 266207, 21139, 44, 144, 252, 266211, 21225731, 233181211211181211O2146Cob(II)alaminFADCob(I)alaminFAD8-OHdGCob(I)alamin8-OHdG301, 32125732116753, 301, 32153, 301, 321167ADPADPMagnesiumChlorineMagnesiumChlorineS-nitrosohomocysteineCystathionine52SOD2Serine171, 178ATPZincZincO3NONOHOClHNO2NO224, 12024, 52, 120, 188CSF1ALBD-dimerINSIFNGCSF1TNFIL2IFNGFibrinogenIL4CRPIL4IL1BHBBINSIL6FibrinogenHbA1cIFNGFibrinIL6IL2IL1BALBICAM1FibrinIFNGHbA1cHBA1IR-ATNFD-dimer65, 12345, 14131710931710918, 45, 191, 236183183, 28531718, 23684, 90, 26884, 90, 268196191, 21016, 218, 322191, 2108714831794196183148123, 326123, 32616, 87183, 28565, 12316, 34, 44, 230, 279...16, 45, 94, 268141156, 268Riboflavin71O2 S-AdenosylmethionineMethionine S-Adenosylmethionine S-Adenosylhomocysteine S-AdenosylhomocysteineMethionine72, 15772, 213, 31911, 72, 278, 32131972, 278, 32172, 157ADPNitrotyrosineNitrotyrosineONOO/ONOOHTetrahydrobiopterin4040154ATPATPGlucoseGlucoseFructosamineFructosamine84, 31710910984, 317IronIron121121FLAD179, 163

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